| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Charleston | 9 | 7 | 2 | 0 | 27:7 | 20 | 23 | |
| 2. | Indy Eleven | 8 | 6 | 1 | 1 | 14:6 | 8 | 19 | |
| 3. | Detroit | 8 | 6 | 1 | 1 | 12:4 | 8 | 19 | |
| 4. | Tampa Bay | 9 | 5 | 2 | 2 | 20:14 | 6 | 17 | |
| 5. | Louisville City | 9 | 5 | 1 | 3 | 14:12 | 2 | 16 | |
| 6. | Pittsburgh | 9 | 5 | 0 | 4 | 11:9 | 2 | 15 | |
| 7. | Miami FC | 9 | 4 | 2 | 3 | 16:17 | -1 | 14 | |
| 8. | Rhode Island | 8 | 3 | 4 | 1 | 13:7 | 6 | 13 | |
| 9. | Loudoun | 10 | 1 | 7 | 2 | 15:17 | -2 | 10 | |
| 10. | Birmingham | 9 | 1 | 5 | 3 | 7:9 | -2 | 8 | |
| 11. | Hartford Athletic | 7 | 1 | 5 | 1 | 6:9 | -3 | 8 | |
| 12. | Brooklyn | 8 | 2 | 1 | 5 | 6:8 | -2 | 7 | |
| 13. | Sporting Jax | 9 | 1 | 3 | 5 | 16:28 | -12 | 6 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 9 | 5 | 3 | 1 | 14:8 | 6 | 18 | |
| 2. | Colorado Springs | 9 | 5 | 2 | 2 | 18:11 | 7 | 17 | |
| 3. | FC Tulsa | 9 | 4 | 3 | 2 | 10:6 | 4 | 15 | |
| 4. | New Mexico | 7 | 4 | 2 | 1 | 12:8 | 4 | 14 | |
| 5. | Sacramento Republic | 7 | 4 | 1 | 2 | 11:7 | 4 | 13 | |
| 6. | Lexington | 8 | 4 | 1 | 3 | 13:10 | 3 | 13 | |
| 7. | Monterey Bay | 9 | 4 | 1 | 4 | 11:10 | 1 | 13 | |
| 8. | Phoenix Rising | 9 | 3 | 4 | 2 | 15:12 | 3 | 13 | |
| 9. | Oakland Roots | 9 | 3 | 3 | 3 | 11:11 | 0 | 12 | |
| 10. | Orange County SC | 6 | 3 | 2 | 1 | 7:4 | 3 | 11 | |
| 11. | Las Vegas Lights | 7 | 3 | 2 | 2 | 9:7 | 2 | 11 | |
| 12. | El Paso | 7 | 2 | 2 | 3 | 12:16 | -4 | 8 |